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Muscle catabolism

Muscle catabolism


Loss of lean muscle mass is also called muscle catabolism, it is a process of demolition of voluntary skeletal muscle tissues, which can be induced by different factors both endogenous, i.e. inside the body, and exogenous, i.e. external, as best we will see later in this article. Normally in athletes what determines muscle catabolism is a decompensation between tissue damage induced by physical exercise and inadequate nutrition both from the point of view of carbohydrate and protein intake. However, there are other factor that can determine this condition, see some chronic diseases, the excessive use of alcoholic beverages and even overtraining, the latter we will address in detail.

Muscle catabolism in sport, because it occurs

As we said above, one of the main causes of muscle mass destruction is excessive training or inadequate nutrition, or even the combination of both. For example, the lack or insufficiency of carbohydrates during physical performance can give rise to two different events that both lead to muscle catabolism, let's see them together:

             increase in the oxidation of amino acids (for energy purposes) obtained from protein foods and which therefore cannot be used as plastic substrates to assist muscle protein turnover;

             increase in muscle proteolysis promoted by the depletion of glycogen stores, this glucose polymer which, stored in the liver and muscles, represents the main form of energy that the body uses for its needs.

However, one very important thing should be pointed out, if the protein catabolism is induced by a physical performance not adequately compensated with nutrition, the muscle groups affected by the demolition process will only be those involved in the athletic gesture, unlike what happens instead if the catabolic process is induced by other factors not inherent in physical effort.

Weight loss diet and muscle catabolism

Another interesting factor and directly connected with the loss of muscle mass is the weight loss diet that many bodybuilders, but also other types of amateur and professional athletes, follow to decrease body fat in an attempt to enhance muscle separation by obtaining a denser, more sculpted physique. he is hot. All this on paper seems to have a reasonable motivation, but in reality very often the attempt to lose weight also leads to the loss of muscles and with a higher ratio compared to fat, let's see why. Even a healthy athlete who eats properly can run into catabolism, this happens mainly when eating excessively restrictive carbohydrate intake, a diet that is commonly known as "low carb". Carbohydrates are essential for cellular respiration and prevent too many amino acids from being oxidized in the gluconeogenesis process which transforms them into energy when glycogen stores are depleted or low. The body's response in the absence of carbohydrates is the release of some hormones including catecholamines, glutathione and cortisol, all substances that our body produces in response to strong psychophysical stress. While some of these hormones can induce lipolysis, that is the degradation of fats, on the other hand they are also responsible for the demolition of lean muscle mass, so they should be kept under strict control if you follow a very restrictive diet. The body's response in the absence of carbohydrates is the release of some hormones including catecholamines, glutathione and cortisol, all substances that our body produces in response to strong psychophysical stress. While some of these hormones can induce lipolysis, that is the degradation of fats, on the other hand they are also responsible for the demolition of lean muscle mass, so they should be kept under strict control if you follow a very restrictive diet. The body's response in the absence of carbohydrates is the release of some hormones including catecholamines, glutathione and cortisol, all substances that our body produces in response to strong psychophysical stress. While some of these hormones can induce lipolysis, that is the degradation of fats, on the other hand they are also responsible for the demolition of lean muscle mass, so they should be kept under strict control if you follow a very restrictive diet.

Muscle catabolism in vegans

For those who are vegan and practice sports, the possibility of experiencing a significant decrease in lean muscle mass is far from remote, which is not the case for those who are sedentary and follow a vegan diet, however varied and well-sized. This can happen because the quantities of bioavailable essential amino acids are low in those subjects who do not eat animal foods, we must exclude from this category vegetarians who do not eat meat but other animal sources do (see milk, eggs, etc.). If you practice intense, constant and prolonged sports activities and do not eat animal foods, it is very likely that your muscle mass will not only not increase but will gradually decrease over time. This is not only due to a lack of certain plastic nutrients in males, but also the almost total absence of cholesterol, a fat that is too demonized by the media but which actually performs very precious functions. In fact, cholesterol, in adequate and not excessive quantities, is very useful, it is in fact used as a basic substrate for the natural synthesis of testosterone, a very powerful male hormone with an anabolic and androgenic effect. It is no coincidence that men who have been following a vegan diet for years have deficiencies in this hormone and develop feminization conditions characterized by decreased libido, loss of muscle mass and body hair and clearing of the voice. it is in fact used as a basic substrate for the natural synthesis of testosterone, a very powerful male hormone with an anabolic and androgenic effect. It is no coincidence that men who have been following a vegan diet for years have deficiencies in this hormone and develop feminization conditions characterized by decreased libido, loss of muscle mass and body hair and clearing of the voice. it is in fact used as a basic substrate for the natural synthesis of testosterone, a very powerful male hormone with an anabolic and androgenic effect. It is no coincidence that men who have been following a vegan diet for years have deficiencies in this hormone and develop feminization conditions characterized by decreased libido, loss of muscle mass and body hair and clearing of the voice.

Overtraining and stress muscle catabolism

Another condition that determines the process of destruction of muscle mass that is not adequately compensated is overtraining, also called overtraining. It is a condition in which the body is no longer able to fully recover from the physical efforts made and therefore, instead of obtaining the maintenance or increase of muscle mass, the exact opposite is achieved. Not only that, in cases of severe overtraining there is also a situation of excessive presence of cortisol, a hormone, also known by the term "stress hormone", which has a strong proteolytic component, that is, it is able to promote the degradation of muscle mass. slim. Nevertheless, we must remember that cortisol is a necessary compound for our body since it performs important functions, therefore, when we are talking about cortisol linked to muscle catabolism, we must necessarily speak of excess cortisol. As proof of the above it should be noted that some athletes, who use drugs, try to completely eliminate the presence of the hormone but this is a gross error as in this way functional problems can occur, but this is another matter.Here is a small list of symptoms that may make you think you are overtrained:

             chronic fatigue and decreased physical strength even in the presence of adequate nutrition and rest;

             frequent gastrointestinal arrhythmias and disorders;

             loss of appetite, insomnia and muscle soreness;

             loss of motivation and self-esteem;

             depression and sadness.

Common symptoms of muscle catabolism

As for the possible symptoms of muscle catabolism, it must be said that these are obviously correlated with the sudden and, in some cases localized, loss of muscle mass, so we can list them as follows:

             general decrease in lean muscle mass;

             localized reduction of lean muscle mass;

             weakness in one or more both lower and upper limbs;

             very prolonged physical inactivity;

             difficulty in equilibrium including ambulatory and not only in physical performance;

             lack of desire to train.

Insulin and muscle catabolism

There is another interesting aspect to consider when it comes to proteolysis and muscle catabolism, we talk about the release of insulin. Insulin is a highly anabolic hormone that is usually produced in response to too high a blood sugar. When too many fast-absorbing carbohydrates are consumed, the body produces the hormone that regulates blood sugar levels to avoid hyperglycemia. The problem, however, arises from the moment that insulin leads blood sugar levels to too low quantities and therefore cortisol is produced to demolish muscle mass and use amino acids to rebalance blood sugar. This is why you should alway check the type of carbohydrates you consume in your diet, preferring slow-release carbohydrates such as rye or oats.

Night muscle catabolism: what's true?

Many athletes, especially those who are more attentive to diet, recovery and training, fear that muscle catabolism may occur during the night, as you cannot eat while you sleep. With regard to this discourse, it is necessary to remember that, although the lack of carbohydrate and protein intake can give rise to catabolism, it is also true that avoiding sleeping peacefully in order to continue to eat even at night, would have greater negative effects. In fact, the lack of sleep leads to a series of conditions that certainly do not help the increase of muscle mass, on the contrary, they severely hinder it. Think again about the release of cortisol, a powerful catabolic hormone, or to the tiredness that would be felt the following day and that would undoubtedly have a negative impact on training. So how can we reduce nocturnal catabolism as much as possible? Simple, eat some food before bed and don't worry too much about the little mass you may lose during the night as the positive aspects of a restful sleep will certainly be greater.

How to counteract the loss of muscle mass?

Before seeing what are the possible strategies to avoid losing muscle mass, we must remember that a minimum of loss, although temporary, will always be there as it is induced by normal and physiological protein turnover. Having said this, the first factor that must be observed in relation to the preservation of muscle mass is undoubtedly nutrition, since it is precisely the lack of an adequate diet that is the main factor that determines the loss of lean muscle mass. Obviously, the type of diet you follow must also be sized according to the type of training you do and also to your lifestyle, if for example you train for 10 hours a week and do a strenuous job, you will certainly need a higher calorie and protein intake than a person who trains for 5 hours a week and performs administrative work sitting at a desk. Recovery also plays a fundamental role in the maintenance and / or increase of lean muscle mass and not only for the reasons, related to cortisol, which we talked about above, but also because it is while we sleep that the body makes a particular effort to regenerate the muscle tissues damaged by training. Last but not least, the release of some anabolic hormones that occurs in the first hours of deep sleep, see testosterone and natural gh, two compounds that give a hand to protein synthesis and therefore to the reconstitution of muscle tissue. but also because it is while we sleep that the body makes a particular effort to regenerate the muscle tissues damaged by training. Last but not least, the release of some anabolic hormones that occurs in the first hours of deep sleep, see testosterone and natural gh, two compounds that give a hand to protein synthesis and therefore to the reconstitution of muscle tissue. but also because it is while we sleep that the body makes a particular effort to regenerate the muscle tissues damaged by training. Last but not least, the release of some anabolic hormones that occurs in the first hours of deep sleep, see testosterone and natural gh, two compounds that give a hand to protein synthesis and therefore to the reconstitution of muscle tissue.

Use food supplements to counteract muscle catabolism

As always, supplements, if used properly, can help and support results, but only if they are taken in a certain way and not considered as a substitute for the normal diet. In fact the supplement must add what is missing in your diet, as long as there is something missing in your diet, this is obvious. In this particular case we can mention three types of supplements that can be a valuable aid in combating muscle catabolism, and therefore:

             energy supports to make the best use of glycogen stores in the synthesis of Atp, we are therefore talking about creatine and magnesium which are directly connected with the release of cellular energy;

             branched bcaa and essential amino acid pools, to be used if, for any reason, it is not possible to reach the optimal protein content with the diet;

             specific compounds against proteolysis, see KIC, HMB and phosphatidylserine , the latter very valid for counteracting the presence of cortisol;

             slow-release proteins , ideal to be taken in the evening before bed to provide the body with adequate plastic substrate during the hours of sleep.

There are also numerous other nutrients that can be, even indirectly, of help in countering muscle catabolism, let's make an exhaustive list:

             carnitine , a compound that, where there are low amounts of glycogen, helps the oxidation of fats to transform them into energy and at the same time decreases the potential catabolism induced by the oxidation of amino acids, another form of energy alternative to glycogen;

             hormonal stimulators of testosterone and GH such as tribulus terrestris , Peruvian maca and citrulline, nutrients that will optimize the blood levels of anabolic hormones, helping to preserve muscle mass;

             vitargo and other rapidly absorbed carbohydrates, to be used before and during prolonged and intense physical activities to prevent the lack of sugar from inducing hypoglycemia which, in turn, is a reason for the release of cortisol.

In summary 

             it is a decrease in lean muscle mass induced by inadequate nutrition or other pathological or external factors to the body;

             it can occur in both sports and sedentary subjects;

             intense and prolonged training causes it momentarily;

             an adequate diet is essential to compensate for physical effort and avoid catabolism;

             the lack of night rest is a reason for triggering muscle proteolysis and therefore catabolism;

             some hormones support muscle growth while others, such as cortisol, hinder it;

             for those who are vegan and practice sports, muscle catabolism is a common condition;

             food supplements can help avoid catabolism and maintain lean mass.